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  5. Pumpkin seed 20:1 concentrate

Specialized botanical

Pumpkin seed 20:1 concentrate

A 20:1 pumpkin seed concentrate, rich in β-sitosterol, phytosterols, and cucurbitin — addressing the male DHT-driven hair-loss factors².

Cucurbita pepo L.

Specialized botanical · measurable at 24 weeks¹

2026-05-24
+40%¹
Hair count

Cho 2014, n=76 men, 24 wk

Specialized botanicalDHT defense
References←All research
Science card for Pumpkin seed 20:1 concentrate

Why this matters

Male hair loss mostly comes back to one name — DHT. It is not a disease, but a male hair-loss factor within the body; for some scalps, some follicles, its influence shows more plainly than for others.

Pumpkin seed 20:1 concentrate is the second DHT-defense research base in this formula — set alongside saw palmetto, each carrying its own 24-week human study. Putting two independent research bases in one formula isn't about being louder; it's about making the coordinates clearer.

A traditional edible seed from North America

Pumpkin seed has travelled a long road in the diet of North America. First as seed, as food, as a kitchen staple; only later as research material. The Latin name Cucurbita pepo L. — appearing once is enough.

What we chose is a 20:1 concentrate, standardized on β-sitosterol as its marker. This means the measurable active compounds of twenty parts of raw material are compressed into the density of one part of finished product. A powder, a dry concentrate — not the pumpkin seed oil common on the market.

What should be stated up front — the study most often cited to date (Cho 2014)³ enrolled only 76 men. Female users' response was not validated in that study. This botanical goes into the formula because its research coordinates are clear enough — but which population those coordinates belong to, we'll say up front, not hide in the back.

Aligned to the β-sitosterol standardisation grade of the studied active — the same research-grade standard. On form, the study used pumpkin seed oil; we use a 20:1 dry concentrate — what aligns is the measurable level of β-sitosterol, not the form.

The research data

This study ran 24 weeks at a dose of 400 mg of pumpkin seed oil (PSO) per day, with 76 participants — all men with visible signs of hair loss³. The investigators set three directions of observation: clinical assessment, user self-assessment, and an actual count of hair density.

More from the research

Science card for Italian Annurca apple

Italian Annurca apple

Malus pumila Mill. cv. Annurca

Science card for Ashwagandha

Ashwagandha

Withania somnifera

Science card for Saw palmetto extract

Saw palmetto extract

Serenoa repens (W. Bartram) Small

Science card for Mixed tocotrienols

Mixed tocotrienols

Elaeis guineensis Jacq.

  1. Based on human research data.
  2. Product results vary between individuals.
  3. Specialised botanicals — single-study evidence.

References

  1. Cho YH, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med. 2014;2014:549721. PMID: 24864154

All three directions showed improvement. The most often externally cited +40% hair count comes from the last — that is, a gap of about +10% relative to the placebo group (P<0.001).

  • Hair count: pumpkin seed oil group +40% / placebo group +10% (Cho 2014, n=76, 24 wk)
  • Clinical assessment: positive change
  • User self-assessment: positive change

What this study can tell you — under the conditions of men, 24 weeks, 400 mg of pumpkin seed oil per day, this botanical's research coordinates are clear. What it cannot tell you: female users' response, which this study did not validate; we won't tell you “research has proven this works for you.” Research is just research — not a word more.

How much a day, and is it enough

After converting the 20:1 concentration ratio back to the equivalent weight of raw material, HairBooster™ sits above the dose used in the Cho 2014 study at both the 1× (maintenance) and 3× (advanced) dose tiers³.

On the question of “is it enough,” the formula-level answer is: it already lands above the dose range used in the published research. The difference in form (the study used oil, we use a dry concentrate) was laid out earlier.

But for some people, this formula isn't suitable — and that has to be said up front, not hidden in the back.

  1. During pregnancy: avoid. This botanical has not been validated as safe during pregnancy.
  2. Trying to conceive (TTC): pause during active conception attempts.
  3. Breastfeeding: use with caution — edible-grade pumpkin seed enters breast milk at very low doses, but there is no corresponding safety data for the supplement form.
  4. Adolescents: 1× with caution, 3× avoid — no adolescent research data.
  5. General adults 18 and over (men / women): both 1× and 3× are within the edible-grade range.

This isn't a warning — it's something this formula is willing to state up front.

What goes in, and what stays out

Pumpkin seed extract comes in no single form on the market — raw seed powder, cold-pressed oil, ethanol extraction, supercritical CO₂, concentrates at different ratios, different standardisation markers, or none. Our choice is set at a position with research coordinates to align to.

Specification is what stays constant about this raw material:

  • Form: 20:1 dry concentrate (powder)
  • Standardisation marker: β-sitosterol
  • Part used: seed

Each batch's β-sitosterol COA data, the full supplier-qualification file, and the “not this extract” distinguishing description — these belong to the raw-material sub-file, currently in development. They'll be made public once the raw-material sub-file lands.

Inside the HairBooster™ formula

Pumpkin seed 20:1 concentrate is one of the two specialized botanicals in this formula — set alongside mixed tocotrienols, each carrying its own coordinates under its own research.

Sharing the formula are three flagship botanicals (Annurca apple, ashwagandha, saw palmetto) and thirteen foundational actives (B-vitamins, iodine, selenium, niacinamide, biotin, zinc, vitamin D3, and more).

Five cores, thirteen foundations — designed, not assembled.

References

  1. Cho YH, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med. 2014;2014:549721. PMID: 24864154
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